Since I am the original poster, I thought I would update the forum on issues with the fix. The program that refused to run was Opera. It is the GUI for my billing system and needs VBS to run. We edited the registry as instructed here but that didn’t fix the problem. We found that in My Computer’s File Types, VBS was set to open with Advansys. We had to change the path and point it to Microsoft Windows Based Script Host (c:windowssystem32cscript.exe). This corrected the problem. We have written a script that can automate this process. They don’t seem to like registry hacks posted here so if the moderator would email me, I can provide the file to them for distribution.