Is the WebBrowser inside an Applet form (i.e TEmbeddedWeb)? If it is inside a form then I think you can use the WebBrowser event to do perform an action.
If the WebBrowser not inside a form then one possibility is to use the Advansys Formativ 2.0.1 API to execute the applet. The Advansys Formativ 2.0.1 API is a COM/XML based API allowing third parties to interact with Formativ from processes external to GroupWise. See the URL below for more information about Formativ API: http://www.advansyscorp.com/forums/topic/4131090521/